abstract：:The effect of leukoaraiosis or white matter low attenuation (WMLA) on cognitive function is not fully understood. We compared the neuropsychological performance of 37 Alzheimer's disease patients with WMLA on CT brain scans with a similar group of 31 Alzheimer's disease patients with no evidence of white matter lesion...

journal_title：Age and ageing

authors： Amar K,Bucks RS,Lewis T,Scott M,Wilcock GK

更新日期：1996-11-01 00:00:00

abstract：:The aim of this study was to evaluate the type and frequency of falls presenting to an inner city casualty department, and to identify modifiable risk factors in these patients. A prospective descriptive study evaluated those over 65 years presenting to an inner city casualty department with falls. Over a 4-week recru...

journal_title：Age and ageing

authors： Davies AJ,Kenny RA

更新日期：1996-09-01 00:00:00

abstract：:This review considers the changes in salivary glands associated with ageing and concludes that there is no evidence to show that xerostomia is likely to result from the ageing process alone. The four main factors causing xerostomia are presented and it can be seen that the condition is a side-effect of diseases and th...

journal_title：Age and ageing

authors： Ettinger RL

更新日期：1996-09-01 00:00:00

abstract：:We examined the characteristics of patients occupying elderly-mentally-ill acute and assessment beds in all mental health units within North and South Thames Regions; the proportion of patients defined as no longer requiring acute care (inappropriately located); and the unmet need for alternative service provision the...

journal_title：Age and ageing

authors： Koffman J,Fulop NJ,Pashley D,Coleman K

更新日期：1996-07-01 00:00:00

abstract：:The type of environmental hazards implicated in the aetiology of a consecutive series of 787 hip-fracture patients was prospectively studied. Most falls occurred between 09 h 00 and midday and there was no seasonal variation. Fifty-one different environmental hazards were implicated in the aetiology of the fall for 58...

journal_title：Age and ageing

authors： Parker MJ,Twemlow TR,Pryor GA

更新日期：1996-07-01 00:00:00

abstract：:To determine whether medication use differs by cognitive status among community dwelling elderly, a survey was made of a stratified random sample of 4110 black and white participants, aged 65 or older from the Duke Established Populations for Epidemiologic Studies of the Elderly in five adjacent urban and rural counti...

journal_title：Age and ageing

authors： Hanlon JT,Landerman LR,Wall WE Jr,Horner RD,Fillenbaum GG,Dawson DV,Schmader KE,Cohen HJ,Blazer DG

更新日期：1996-05-01 00:00:00

abstract：:Resuscitation decisions during the first 6 weeks were analysed for 97 admissions to a psychogeriatric ward of a general teaching hospital. Seventy-seven patients (79%) had a written 'do not resuscitate' (DNR) order on admission and 74 patients (875) had a written DNR order after 6 weeks. Morbidity was assessed with a ...

journal_title：Age and ageing

authors： Dautzenberg PL,Hooyer C,Schonwetter RS,Dermout KM,vd Veer JK,Duursma SA

更新日期：1996-05-01 00:00:00

abstract：:Formal assessment of cognitive decline with cognitive tests can be difficult, requiring either two measurement points or a comparison of 'hold' with 'don't hold' tests. Informant-based assessment provides an alternative approach because informants can adopt a longitudinal perspective and directly rate cognitive change...

journal_title：Age and ageing

authors： Jorm AF,Christensen H,Henderson AS,Jacomb PA,Korten AE,Mackinnon A

更新日期：1996-03-01 00:00:00

abstract：:Myasthenia gravis is probably commoner than previously suspected, the annual incidence being nearer 9-10/million than earlier figures of 2-4/million. The current study found an annual incidence in Croyden of 9.1 per million (95% confidence limits 5.7-13.8 per million). Of the 22 patients (59%) seen in Croyden with new...

journal_title：Age and ageing

authors： Schon F,Drayson M,Thompson RA

更新日期：1996-01-01 00:00:00

abstract：:Lower urinary tract symptoms are frequency report in Parkinson's disease. Whether these are causally related to Parkinson's disease rather than the known effects of age on the urinary tract is unknown. In this study we compared urodynamic data from 1864 women and 357 men with no neurological disease with data from 34 ...

journal_title：Age and ageing

authors： Gray R,Stern G,Malone-Lee J

更新日期：1995-11-01 00:00:00

abstract：:This study aimed to determine the prevalence of the wish to die in elderly people and investigate the factors associated with it, in particular, whether factors other than depression contribute to the wish to die. Data were obtained from an Australian epidemiological survey of people aged 70 or more. Survey participan...

journal_title：Age and ageing

authors： Jorm AF,Henderson AS,Scott R,Korten AE,Christensen H,Mackinnon AJ

更新日期：1995-09-01 00:00:00

abstract：:Hospital-at-Home schemes have been claimed to hasten the discharge of elderly orthopaedic patients, and are becoming increasingly popular with health service managers. In an attempt to measure the benefits of such a scheme when applied to elderly medical patients, we prospectively randomized 60 consecutive referrals o...

journal_title：Age and ageing

authors： Donald IP,Baldwin RN,Bannerjee M

更新日期：1995-09-01 00:00:00

abstract：:A cross-sectional survey of community-dwelling elderly volunteers (104 women, 87 men, mean age 70 years) was carried out in winter to determine whether cardiovascular and other potentially modifiable lifestyle factors were associated with serum levels of 25-hydroxyvitamin D during this period. Mean winter levels of se...

journal_title：Age and ageing

authors： Scragg R,Khaw KT,Murphy S

更新日期：1995-07-01 00:00:00

abstract：:Twenty digitalized elderly patients with chronic atrial fibrillation were randomized into a double-blind cross-over study. None was in overt heart failure and all were taking < 80 mg frusemide daily. They received xamoterol 200 mg b.d. for 2 months with their usual dose of digoxin for 1 month and placebo digoxin for t...

journal_title：Age and ageing

authors： Lawson-Matthew PJ,McLean KA,Dent M,Austin CA,Channer KS

更新日期：1995-07-01 00:00:00

abstract：:The clinical diagnosis of Parkinson's disease may be difficult. In elderly patients there may be other causes of the triad of rigidity, bradykinesia and tremor. This study was designed to assess whether a single levodopa challenge could predict dopa responsiveness in patients with Parkinson's disease. Twenty-two of 27...

journal_title：Age and ageing

authors： D'Costa DF,Sheehan LJ,Phillips PA,Moore-Smith B

更新日期：1995-05-01 00:00:00

abstract：:Many studies have shown the indigenous elderly population and Asian immigrants to be groups at particular risk of vitamin D deficiency and osteomalacia, but there are no data on the risks in elderly Asians. In this community-based study a group of elderly Asians was compared with control groups of elderly and young wh...

journal_title：Age and ageing

authors： Solanki T,Hyatt RH,Kemm JR,Hughes EA,Cowan RA

更新日期：1995-03-01 00:00:00

abstract：:In this study we examine whether the introduction of a clerking pro forma improves the completeness of the recording of the management of stroke patients and we review methodological issues important in this type of audit. We prospectively identified 244 consecutive stroke patients before and after the introduction of...

journal_title：Age and ageing

authors： Davenport RJ,Dennis MS,Warlow CP

更新日期：1995-01-01 00:00:00

abstract：:The relationship between hip fractures and aluminium in antacids and cooking pots was examined in an epidemiological study in Sydney, Australia. A population-based case-control study was conducted and 416 men and women aged 65 years and over were recruited (209 cases and 207 controls). There was a significantly (p < 0...

journal_title：Age and ageing

authors： Cumming RG,Klineberg RJ

更新日期：1994-11-01 00:00:00

abstract：:The aim of this prospective study was to investigate whether an immunological double faecal occult blood test (Fecatwin-S/FECA-EIA) can be used in screening patients with symptoms suggestive of colonic or rectal origin in primary health care. Altogether 523 patients were referred to the study by general practitioners....

journal_title：Age and ageing

authors： Kemppainen M,Häkkinen I,Räihä I,Pomoell R,Sourander L

更新日期：1994-09-01 00:00:00

abstract：:Two hundred and eighteen subjects, out of 250 individuals taken from a general practice register, returned completed questionnaires giving details about rest cramps, and a further 15 were contacted by telephone. The overall prevalence of rest cramps in the survey population was 37%. The symptom was more prevalent in o...

journal_title：Age and ageing

authors： Naylor JR,Young JB

更新日期：1994-09-01 00:00:00

abstract：:Fifty-eight carers and their dependents who received inpatient respite care were studied before and during the admission period. Although there was no observable improvement in the carers' emotional well-being the majority of the patients showed an improvement in functioning, particularly those who were being looked a...

journal_title：Age and ageing

authors： Homer AC,Gilleard CJ

更新日期：1994-07-01 00:00:00

abstract：:Prolonged head-up tilt is increasingly used as a diagnostic test for vasovagal syncope. Its sensitivity is reported to increase with the concurrent administration of intravenous isoprenaline. False-positive responses are common in young controls particularly following intravascular instrumentation. We studied the infl...

journal_title：Age and ageing

authors： McIntosh SJ,Lawson J,Kenny RA

更新日期：1994-07-01 00:00:00

abstract：:The objective of this study was to determine whether the Short-form 36 Health Status Questionnaire (SF-36) is suitable for use in an elderly population. The SF-36 was administered by interview to a random sample of 827 adults from West Glamorgan. Among the 216 adults aged 65 and over the data were 98.8% complete. Evid...

journal_title：Age and ageing

authors： Lyons RA,Perry HM,Littlepage BN

更新日期：1994-05-01 00:00:00

abstract：:The relationship of bone mineral density (BMD) to age and weight was investigated in a cross-sectional study of 942 community-dwelling men and women aged 65-74 years. BMD continues to decline after the age of 65 at a similar rate in men and women. BMD was positively associated with weight in both men and women with si...

journal_title：Age and ageing

authors： May H,Murphy S,Khaw KT

更新日期：1994-05-01 00:00:00

abstract：:We measured calcium regulating hormones and bone mineral density (BMD) in 66 men (aged 24-88 years). Vitamin D (1,25(OH)2D) does not vary with age, parathyroid hormone (PTH) increases after the age of 65 (p < 0.01) together with a parallel increase in urinary (r = 0.46, p < 0.05) and nephrogenic cAMP (r = 0.63, p < 0....

journal_title：Age and ageing

authors： Ravaglia G,Forti P,Pratelli L,Maioli F,Scali CR,Bonini AM,Tedioli S,Marasti N,Pizzoferrato A,Gasbarrini G

更新日期：1994-03-01 00:00:00

abstract：:To learn whether the percentage of time spent at different functional levels varies as a function of age, we studied 44 older (mean age 70 years) and 46 younger (mean age 27 years) urban, community-dwelling volunteers who participated in a study of normative ageing of the cardiovascular system. Each subject completed ...

journal_title：Age and ageing

authors： Ashworth JB,Reuben DB,Benton LA

更新日期：1994-01-01 00:00:00

abstract：:The DOMINO study compared domiciliary and hospital-based rehabilitation services for stroke patients after discharge from hospital, stratified by the hospital ward at discharge. No difference between the services had been found at 6 months, but home therapy was better than outpatient department therapy at improving ho...

journal_title：Age and ageing

authors： Gladman JR,Lincoln NB

更新日期：1994-01-01 00:00:00

abstract：:The difficulties of 24-hour urine collection are well recognized, especially for elderly people for whom a means of estimating protein excretion from a single casual unit sample would be preferable. We compared measurement of total urinary protein estimated by the protein/creatinine ratio with 24-h urine collection an...

journal_title：Age and ageing

authors： Mitchell SC,Sheldon TA,Shaw AB

更新日期：1993-11-01 00:00:00

abstract：:Seventy-nine patients with probable Alzheimer's disease were enrolled into a double-blind, placebo-controlled cross-over study to assess the therapeutic effect and safety of THA (tetrahydroaminoacridine; tacrine) without concomitant lecithin administration. Forty-one patients completed the trial which consisted of two...

journal_title：Age and ageing

authors： Wilcock GK,Surmon DJ,Scott M,Boyle M,Mulligan K,Neubauer KA,O'Neill D,Royston VH

更新日期：1993-09-01 00:00:00

abstract：:The medical histories of 178 colorectal cancer patients were studied retrospectively from hospital records. The average age at the time of diagnosis was 71 years. Visible loss of blood or anaemia were the commonest features. The mean time from first symptom to first medical consultation was 82.8 days. Men under 65 yea...

journal_title：Age and ageing

authors： Kemppainen M,Räihä I,Rajala T,Sourander L

更新日期：1993-07-01 00:00:00

abstract：:A study was carried out to examine the prevalence of oropharyngeal and urinary tract colonization and to compare the colonizing bacteria with the strains causing nosocomial infections during patients' stays in a geriatric ward. Colonization with Gram-negative rods was not uncommon. Nosocomial infections frequently occ...

journal_title：Age and ageing

authors： Michielsen W,Vandevondele D,Verschraegen G,Claeys G,Afschrift M

更新日期：1993-05-01 00:00:00

abstract：:Energy intake and resting energy expenditure in relation to body composition were studied in female patients with Alzheimer's disease, multi-infarct dementia and in home-living non-demented elderly women. Patients with Alzheimer's disease tended to have lower body weight and higher energy intake (p = NS) than control ...

journal_title：Age and ageing

authors： Niskanen L,Piirainen M,Koljonen M,Uusitupa M

更新日期：1993-03-01 00:00:00

abstract：:One hundred and sixty centenarians were discovered and followed up for 7 years (1982-88) in Shanghai. The proportion of centenarians in the population was non-significantly greater in the urban than in the rural area and centenarians were in general increasing in both areas over the years. The factors promoting longev...

journal_title：Age and ageing

authors： Zheng ZX,Wang ZS,Zhu HM,Yang JY,Peng HY,Wang LX,Li J,Jiang XW,Yu YF

更新日期：1993-01-01 00:00:00

abstract：:Interest in, and concern about, the abuse of elderly people is growing rapidly. A study of the literature shows little research in the UK, but valuable indicators about risk factors and interventions from North America. One of the major problems has been definition and this paper distinguishes between different kinds ...

journal_title：Age and ageing

authors： McCreadie C,Tinker A

更新日期：1993-01-01 00:00:00

abstract：:This study describes a survey of 256 informal carers and elderly people they support, and examines the impact of the caring role upon quality of life. Carers reported that many aspects of their physical and mental health as well as their social and family lives were affected by their caring. For many the caring activi...

journal_title：Age and ageing

authors： Jones DA,Peters TJ

更新日期：1992-11-01 00:00:00

abstract：:The aim of the present study was to determine the prevalence of biliary lithiasis (BL) and its major associated factors in the elderly people of a small town in Sicily. All inhabitants over the age of 65 were interviewed and underwent a general physical examination, blood tests and ultrasonography of the gallbladder a...

journal_title：Age and ageing

authors： Montalto G,Soresi M,Carroccio A,Averna MR,Muratore R,Li Castri C,Barbagallo CM,Cavera G,Sapienza M,Notarbartolo A

更新日期：1992-09-01 00:00:00

abstract：:Clinical observations suggest an age-associated decline in skin perfusion but there are few quantitative in vivo data on skin perfusion at various ages. We studied skin perfusion of the dorsum of the foot by determining the capillary blood flow velocity (CBFV) expressed in millivolts (mV), using laser Doppler flowmetr...

journal_title：Age and ageing

authors： Weiss M,Milman B,Rosen B,Eisenstein Z,Zimlichman R

更新日期：1992-07-01 00:00:00

abstract：:The cardiovascular responses to tilting and breathing were studied in 24 patients with late-onset Alzheimer's disease (AD) and 54 healthy control women aged between 75 and 96 years in order to study the parasympathetic and sympathetic heart-rate control. The cardiovascular response to tilting and breathing showed no a...

journal_title：Age and ageing

authors： Elmståhl S,Petersson M,Lilja B,Samuelsson SM,Rosén I,Bjunö L

更新日期：1992-07-01 00:00:00

abstract：:One hundred and seventy residents of 11 Leicester City Council homes for the elderly, with a total of 515 beds, were studied during a 30-week period from September 1988 to March 1989 to determine the use of influenza vaccine, the levels of influenza antibody, the incidence of influenza, and the protection afforded by ...

journal_title：Age and ageing

authors： Nicholson KG,Baker DJ,Chakraverty P,Farquhar A,Hurd D,Kent J,Litton PA,Smith SH

更新日期：1992-05-01 00:00:00

abstract：:Sleep disordered breathing (SDB) may be associated with cognitive dysfunction in non-demented elderly people. A random sample of 96 retirement village residents were given both neuropsychological assessment and overnight sleep monitoring with a portable microprocessor based system (Vitalog PMS-8). Respiratory disturba...

journal_title：Age and ageing

authors： Hayward L,Mant A,Eyland A,Hewitt H,Purcell C,Turner J,Goode E,Le Count A,Pond D,Saunders N

更新日期：1992-03-01 00:00:00